Preface:
Southwest Nebraska - Zone 5B - I experience all four seasons. Hot summers that can be humid some years. Cold winters.
Designing my home to build. Trying to determine which is the most cost effective method to do the walls. I am young, and intend on living in this house for a very long time.
I have done so much reading on here and other sources that I have honestly confused myself. Sad, isn't it? I realize what works in Florida will not work in Nebraska for example. However there seems to be a lot of controversy. I have read that using anything more than a 2 x 6 stud gives diminishing returns on the extra material cost to using a staggered stud wall system for ultimate insulation.
I am currently thinking I should go with a 2x8 stud wall with 16" o.c. - Whatever wall I choose, I want 16" o.c. for purposes of hanging sheetrock, cabinets, shelves, tvs, etc. 24" o.c. just leaves too big of space for me to consider, even though 2 x 8 with 16" o.c. will...